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Additionally, we found the highest frequency of the 677T allele in the regions where there is the highest incidence of NTDs in Mexican Mestizos (S, CE, and SE) [19, 35] and interestingly, it was consistent with the regions where Amerindian groups made a major contribution to the Mexican gene pool [17, 18, 36]

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However, limited research has examined its translatability and the role of acute GH administration on the human gut microbiome